Tuesday, March 11, 2025

 Magazine link

https://www.apnebalpeh.com/magazine.php

The Unsung Heroes of Society: Three Golden Rules for Researchers

Abrar Hussain

International center for Chemical and Biological Sciences, University of Karachi, Karachi Pakistan.

 

Researchers are the most important yet least appreciated individuals in society. They dedicate their lives to solving problems, uncovering the mysteries, creating innovations, and diagnosing diseases. Their tireless efforts enable us to lead harmonious and fascinating lives, often at the cost of their own well-being.

A researcher’s journey is demanding. Long hours in labs, unrelenting challenges, and constant pressure often lead to frustration, exhaustion, defeat, embitterment, and infuriation. Despite being the critical thinkers, agents of change, and diligent contributors, researchers seldom receive the recognition they deserve. This lack of acknowledgment, combined with the overwhelming demands of their work, can leave them feeling embittered and demotivated.

Recognizing this, I was inspired to explore strategies to support researchers in maintaining consistency, enthusiasm, and a positive outlook. After extensive observation, discussion, reading, and attending various conferences, I developed what I call the Three Golden Rules (3GR)—a set of rules designed to help researchers to have happier and more productive lives. These rules not only aim to combat frustration but also encourage younger researchers to embrace research with passion and purpose.

The Three Golden Rules (3GR) for Researchers

Golden Rule 1: Avoid Comparison

Comparison is often the root of dissatisfaction and frustration. Many researchers fall into the trap of measuring their achievements against others, forgetting that each individual possesses unique skills, strengths, and potential. Embracing one’s own journey, rather than comparing it to someone else’s, fosters self-discovery and satisfaction. Understanding that success takes different forms for different people can lead to a more fulfilling and peaceful mindset.

Golden Rule 2: Embrace Hard Work

The modern emphasis on working smart has often been misinterpreted, leading some to undervalue the importance of hard work. While efficiency is essential, hard work remains the cornerstone of success, especially in research. Dedication and consistent effort not only differentiate one researcher from another but also reduce the burden of unfinished tasks. Hard work and timely completion can ensure progress and build resilience.

Golden Rule 3: Focus on the Process, No-Results Oriented

Research is inherently unpredictable, and results often deviate from initial expectations. This can lead to disappointment or even abandonment of projects. However, patience and perseverance are critical. Sometimes, extraordinary results emerge only after numerous attempts. Additionally, adopting a mindset rooted in faith—understanding that outcomes align with what is destined for us—can provide peace of mind and strengthen resolve. As researchers, we are the tools for discovery, not the sole architects of outcomes. Trusting the process and faith can reorient our focus and enhance our performance.

Conclusion

Practicing non-comparison, embracing hard work, and focusing on the process rather than results can lead the researchers to alleviate stress and rediscover their passion for inquiry. Coupled with time management, patience, and a belief in the role of destiny, these principles offer a framework for leading a more balanced and fulfilling life as a researcher. The 3GR approach encourages researchers to persevere through challenges and find joy in their contributions to society.

Let us support and uplift our researchers, providing them with the encouragement and recognition they truly deserve. Together, we can ensure their invaluable work continues to shape a brighter future for all.

 


Wednesday, December 11, 2024

 



7 Questions on Leadership with Abrar Hussain


Its my honor that a prestigious international organization Clarity Group Global has been published my "7 Questions on Leadership" interview. I I am truly grateful to Jonno White for conducting the interview and sharing it on their website.

Aims and Objective:
The aim of these interviews is to uncover the hidden talents of young individuals and highlight the paths that contribute to reshaping their personalities. These interviews serve as a powerful source of inspiration, encouraging others to step forward and explore their own potential.
Key message of my interview:
I am a research scholar by profession with strong leadership skills. I’ve discovered that many young people possess untapped potential, often due to a lack of resources and poor time management. I believe that waiting for the "perfect time" isn’t necessary—now is the time to explore your hidden potential and make a difference in the world. Consistency is a key trait of a leader, so once you begin exploring an idea, follow it through to completion, undeterred by temporary obstacles. The three golden rules I live by are: work hard, avoid comparison, and maintain strong faith. These principles set you apart from others.

please find the full interview on the website




Saturday, August 24, 2024



https://www.theearthneedslove.com/2024/08/microorganisms-and-climate-change.html 

Microorganisms and Climate Change: The Smallest Doing the Bigger

                                Abrar Hussain (abrarhussain0307@gmail.com)

International Center for Chemical and Biological Sciences, University of Karachi, Pakistan


Microorganisms

Microorganisms are the oldest living creatures in our planet which arise some 3.5 billion years ago. These are the most diverse, abundant, and highly prevalent creature in different environments, being dominated in one place while less somewhere else. Approximately 159,000 different kinds of microorganism’s species are exist, which affect almost every aspect of our lives. Reshaping our personality, affect our mood and physiological functions, combating aging, promoting biotechnological applications, and being used as probiotics are the few diversified areas that are affected by microorganisms. Ranging in their presence in food sources to water, in household to the clinical, and from soil to air, these creatures also have a strong hold on the climate. Currently, microbes are used in plenty of applications that include nutrient recycling, the food industry, agriculture, carbon and nitrogen cycles, and other applications, as summarized in Figure 1. Besides the positive attributes of microorganisms, they are also the vectors of disease transmission and thus cause the deaths of humans, animals, and the environment. Due to their ubiquitous distribution, microorganisms are now considered a potential contributor to climate change.

Figure 1. The important functions and applications of microorganisms

Climate change  

The term climate refers to the long-term weather pattern of a specific region, while climate change describes the long-term changes or shifts in the weather conditions of a particular area. The term climate change was coined by Wallace Broecker (a geochemist) in 1975 to emphasize the importance of global temperature. Soon after, this concept was highlighted at different levels. climate change is an issue of great concern as it affects all aspects of our lives. It reflects global warming and thus becomes a one-point threat to human concerns. It adversely affects our environments and thus the human health through causing change in weather patterns, air pollutions, global warming, destroy the agriculture, lowering food productions, and increasing hunger and inadequate nutrition. Due to its potential impacts on our lives, efforts on every scale are being made to overcome the consequences of climate change. Numerous international, national, organizational, and individual efforts are made to develop strategies, guidelines, and rules that help to lower the effects of climate change. Different approaches and methodologies are proposed that help to understand the exact causative agent of climate change and the ways in which it will work effectively.

Microorganisms and climate change

Highlighting the potential role of microorganisms in our environments, like biodegradation, cleaning, and markers of environmental pollution, these are also considered to play an important role in climate change. Their role in climate change is well recognized, as they reflect different aspects of the environment. But their versatility, greater prevalence, and substantial interactions make it difficult to explore their role in climate change and greenhouse gases. These are involved in the production and utilization of greenhouse gases i.e., carbon dioxide, methane, etc. and hence produce positive and negative effects on climate change. On the other hand, the climate change negatively affects the microorganisms by acidification, warming, and a rough temperature, resulting a misbalance in their ecological distribution.    

The effects of microbes on humans and animals are prominent, indicating their importance in our lives. Similarly, the effect of climate change is not only restricted to a few terms; it covers all the environmental changes that include changes in temperature, pH, and soil topological properties, which in turn affect the microbe’s prevalence and distribution. The warming of the earth leads perishable food, more disease cases, and enhanced natural disasters, which lower the microbe’s activities. Fortunately, the physiological potential of microbes, like their growth properties, greater prevalence, and ability to share genetic information, makes them fit for environmental adaptations. These adaptations take place in several ways, like increasing bacterial respiration, developing proteins that resist environmental conditions, etc., and hence helping the microorganisms to survive during climate change. Viruses also have the potential to show adaptation to the environment being affected by climate change. These changes in microbial biology can have a great impact on humans and other animals.   

Microorganisms are also used as a solution to climate change. It is documented that microbial tools can provide a potential solution for climate change in the environment. These can also provide an intricate line of innovation while addressing climate change issues. Likewise, the soil microbiota brings changes to the plants, like making them more resistant to harsh conditions and increasing productivity, while also protecting plants from different climate change effects. A type of bacteria called Methanotrophs has the potential to reduce the emission of methane, a greenhouse gas, and thus lower the effects of climate change.  The different aspects of microorganisms and climate change are illustrated in Figure 2.

Figure 2. The different aspects of microorganism, climate change, their interactions and solutions.

Humans' activities produce the greenhouse gases (GHG) in large quantities and thus cause change in the climate. Microorganisms can consume these GHGs when they are required for their growth. Despite being pathogenic microorganisms that cause several diseases, other microbes are adversely affected by climate change and ultimately human activities. In the case of pathogenic microbes, climate change can lower their prevalence and hence decrease the burden of infectious diseases.    

The high temperature due to climate change can affect the long-term transport of pathogens and change their prevalence. The scenario becomes more adverse in terms of opportunistic pathogens. There are many ways in which these microbes can fight climate change. These include the conversion of carbon into organic matter, the nitrogen cycle (an important nutrient in plant growth), supporting plant growth, recycling soil nutrients, and reducing soil pollution by lowering the toxic chemicals in the soil. The development of smart agriculture approaches also lowers the effects of climate change.

Conclusion

Microorganisms are the smallest creatures that have existed since billions of years ago. These have a potential effect on humans, animals, and environments. Greater prevalence, versatile nature, dynamic physiological characteristics, rapid growth, and both beneficial and pathogenic nature make microbes an important agent of our biosphere, which cannot be neglected. Recently, climate change and its associated phenomena, i.e., global warming and greenhouse gas production, got special attention due to their substantial effects on humans. Besides plenty of other players in climate change, microorganisms are also included. Microbes have the smallest size but have a bigger effect as they directly affect humans' lives. Both positive and negative effects are identified for both climate change and microorganisms. On the one hand, the microorganisms show adaptations to climate change and thus create resistance; on the other hand, they help to overcome the negative impacts of climate change. In conclusion, microorganisms play an important role in climate change, either by producing resistance in plants or by developing adaptations.

Further reading

1-      https://www.nature.com/articles/s41579-019-0222-5

2-      https://www.ncbi.nlm.nih.gov/books/NBK580166/

3-      https://journals.asm.org/doi/pdf/10.1128/mbio.00800-22

4- https://www.hilarispublisher.com/open-access/prevalence-of-microorganisms-in-indoor-household-environments-and-their-pathogenesis-105312.html

5-      https://doi.org/10.3390/microbiolres14030064


Thursday, June 27, 2024

The Human Microbiome and Personality Traits

Abrar Hussain

International Center for Chemical and Biological Sciences, University of Karachi, Karachi Pakistan

Microorganisms have a ubiquitous distribution and are found in all environmental niches with different capacities and concentrations, making an approximate number of 159,000 species. Bacteria, fungi, algae, viruses, etc. are different types of microorganisms that contribute to different processes. Before the identification of their biotechnological applications, these were considered pathogens, and everyone tried to stay away from them. It’s just the game of a few centuries that changed the whole paradigm, and a large population shifted to use them as positively as possible. Probiotics, which are live microorganisms with beneficial properties, are just a glimpse of this potential. It’s the glory of genetic techniques and biotechnology—the combinatorial approach that both enhanced their usage and identified new applications, besides understanding their proper nature and potential. The collection of microorganisms associated with one particular object is called the microbiome, or microbiota. As described, these microbes are also found in humans, with full pros and cons.

Humans, which are the cream of creation and the most advanced creatures of ALLAH (GOD) in the universe, are the most important integrity of anything, anytime, and anywhere. Diving deep into the human body just reflects the intricate nature, super coordination, and extreme advanced systems. Any minute disturbance can have a huge impact on the whole body. Now it’s the power of thrilling thirst that shows how someone interlinked the two extremes—the human and the microorganisms. It’s the fact that the human body is like a ball diving in a sea of microorganisms, with approximately one human cell per 10 microorganisms. Just for curiosity, the human gut microbiota has 1014 microbes with 1000 different species, and hence the game starts over here.

Looking critically and asking a question, can this sea of microbes in and/or on the human body have nothing to do with the physiology, psychology, and behavior of the individual? Honestly, the answer is no; these microorganisms played a pivotal role in the mentioned domains of a person's life. Its mow experimentally validated that gut microbiota play a significant role in the physiological status of the animals. The concept of gut-brain axis arises from another mind-blowing research study in which gut microorganisms signify their value in brain and mind functions. Advancing more, these microbes, which are generally called psychobiotics, have potential effects on the treatment of neuropsychological disorders and help with cognition.

Scientifically, it has now been shown that different personality traits are associated with the presence of different microorganisms in the gut. In research, it was identified that both gut microbiome composition and diversity are related to differences in personality like sociability and neuroticism. For instance, it was documented that a person with a large social circle had a diverse microbiome with good health, in contrast to a depressed person, who had lower microbial diversity. Likewise, mood, behavior, stress, and other cognitive functions are affected by the gut microbiota and thus reflect personality traits. Likely, the skin microbiota, which also has diverse bacteria, can affect the appearance of a person. Currently, the modern living style of fewer interactions may create dysbiosis in the gut, thus leading to different consequences. 

In conclusion, both humans and microorganisms are the unique creatures of ALLAH, the one with the most sophisticated and complex nature, while the other with the extreme small size and simplest structure. Although both are crucial and utmost important for each other and greatly affect one another’s functions. 

References and further readings

1.       Hussain, A., Rahman, M., Bibi, T., Fatima, R., Arif, I., Barwant, M. M., & Ali, S. A. (2024). Prevalence of Microorganisms in Indoor Household Environ-ments and their Pathogenesis.

2.       Johnson, K. V. A. (2020). Gut microbiome composition and diversity are related to human personality traits. Human Microbiome Journal, 15, 100069.

3.       https://www.researchgate.net/publication/378625269_The_Friendly_Microbes_the_Probiotics

4.       https://abrarhussain0307.blogspot.com/

5.       http://dx.doi.org/10.13140/RG.2.2.19473.20325


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