My Research Journey in Probiotics and Microbial Biotechnology: A 2025 Recap of Research and Review Articles

Introduction

I am a researcher working at the interface of probiotics, microbiome science, and microbial biotechnology, with a strong interest in translating fundamental microbial research into practical health, environmental, and industrial applications. Over the years, my work has focused on understanding how beneficial microorganisms—and their bioactive derivatives—can be harnessed to improve human health, support sustainable technologies, and address real-world biological challenges.

This blog brings together a series of my recent review and research contributions that collectively explore the multifaceted roles of probiotics, postbiotics, and functional microorganisms. These works span diverse yet interconnected themes, including advanced probiotic delivery systems such as encapsulation and nanoprobiotics, functional characterization of Enterococcus faecium strains, and the emerging concept of gerobiotics for healthy aging. I also examine microbiome-based strategies for managing complex conditions such as diabetic foot ulcers, highlighting the therapeutic potential of probiotics beyond gut health.

Beyond clinical and nutritional applications, my work extends into environmental and industrial microbiology, particularly microbial biomining as a sustainable alternative to conventional metal extraction. Additionally, I explored the intersection of faith, fasting, and health, integrating scientific evidence with traditional practices, and investigated probiotic and postbiotic interventions for improving honeybee health and preventing economically significant diseases.

Together, these studies reflect my broader research vision: to advance evidence-based, safe, and sustainable microbial solutions that contribute to human health, environmental resilience, and global food security. Through this blog, I aim to communicate scientific insights in an accessible way and highlight the growing impact of microbial science across disciplines. The publication details with brief summary are outlined here:

Summary of research and review publications in 2025.

1.    Encapsulated Probiotics and Nanoprobiotics – Biocompatible Materials, Processing Technologies, and Applications: A Review

Link: https://doi.org/10.17305/bb.2025.13322

Summary:

This review comprehensively discusses encapsulated probiotics and nanoprobiotics, focusing on biocompatible materials such as polysaccharides, proteins, and lipids, along with encapsulation techniques including spray drying, extrusion, and nanoencapsulation. It highlights how these technologies improve probiotic survival, targeted delivery, and therapeutic efficacy, with applications in food, pharmaceuticals, and personalized medicine.

2. Postbiotic Production, Aggregation Properties, Binding Potential, Antioxidant Capacity, and Functional Characterization of Lead Enterococcus faecium Probiotic Strains

Link: https://doi.org/10.3934/microbiol.2025035

Summary:

The study evaluates postbiotic production and key functional attributes of selected Enterococcus faecium strains, including auto-aggregation, adhesion-related binding potential, and antioxidant capacity. The results demonstrate strain-specific multifunctional properties, supporting their potential use as safe and effective probiotic and postbiotic candidates in health-promoting applications.

3.  Deciphering the Anti-Aging Potential of Probiotics: A Narrative Review on Gerobiotics

Link: https://doi.org/10.1016/j.microb.2025.100607

Summary:

This narrative review explores the emerging concept of gerobiotics—probiotics that promote healthy aging. It discusses molecular mechanisms including oxidative stress reduction, immune modulation, gut barrier enhancement, and metabolic regulation. The review highlights preclinical and clinical evidence supporting probiotics as promising interventions against age-related disorders.

4.      The Emerging Role of Probiotics in the Management and Treatment of Diabetic Foot Ulcer: A Comprehensive Review

Link: https://doi.org/10.3934/microbiol.2025027

Summary:

The review summarizes current evidence on the role of probiotics in managing diabetic foot ulcers. It highlights mechanisms such as pathogen inhibition, inflammation control, angiogenesis promotion, and tissue regeneration. Probiotics emerge as promising adjunct therapies to conventional wound management strategies.

5.      Harnessing Microorganisms for Biomining: Unveiling the Power of Microbial Mining

Link: https://doi.org/10.21124/tes.2025.133.145

Summary:

This review discusses the principles of biomining, focusing on microbial mechanisms involved in metal solubilization and recovery. It highlights the role of acidophilic and chemolithotrophic microorganisms in extracting valuable metals, presenting biomining as an environmentally sustainable and economically viable mining strategy.

6.      Fasting at the Confluence of Faith and Health: A Comprehensive Review

Link: https://doi.org/10.22038/JNFH.2025.86766.1571

Summary:

The review explores fasting practices across different faiths and examines their health impacts, including metabolic regulation, oxidative stress reduction, immune modulation, and gut microbiome remodeling. It provides scientific insights into how faith-based fasting can contribute to physical and mental well-being.

7.      Probiotics and Postbiotics: A Promising Prophylactic Measure for American Foulbrood and European Foulbrood Diseases of Honeybees

Link: https://doi.org/10.22038/jnfh.2025.86766.1571

Summary:

The review discusses the application of probiotics and postbiotics in preventing foulbrood diseases in honeybees. It highlights mechanisms such as pathogen suppression, immune stimulation, and microbiota balance, presenting these biotherapeutics as eco-friendly alternatives to antibiotics in apiculture.

Conclusion:

Collectively, these works highlight the expanding potential of probiotics, postbiotics, and functional microorganisms across health, biotechnology, and sustainability. By integrating advanced delivery technologies, functional microbial characterization, and interdisciplinary applications, this body of research underscores the promise of microbiome-based strategies in addressing clinical challenges, environmental needs, and future therapeutic innovations.